Ōsaka (大阪) is the beating heart of Japan's Kansai region and the largest of the Osaka-Kobe-Kyoto trio of cities, with a population of over 17 million people in the greater metropolitan area. With fantastic food and nightlife, great connectivity and accommodation options in every price bracket, it makes a great base for exploring the entire region.
Source: Wikivoyage (CC BY-SA)